Cannabis Oil Dosage

The future of successful Dosing “Competitive Inhibition”
By Phil Feco -including compilation of research by Dominic Le Prevost and other Doctors.

This is the protocol I follow (please read disclaimer at the bottom of this post)

Coconut Oil & Olive Oil in regards to the different ways they will take the Cannabis Oil through your system. This is about blending Cannabis Oil made from solvents. Placing in a capsule and orally ingesting.

A lot of people have trouble with the euphoric effects felt from oral dosing. Suppositories are suggested as to alleviate this ‘high ‘effect. But what if you could dose orally with a highly bio-available oil and have less euphoric effects. Keeping the oil away from the liver is key. It will eventually get to the liver if it has not attached to any receptors along the way.

The oil when made the 'traditional way', the potency and medicinal value that the resulting concentrate contains, is simply not very bio-available. 
Meaning, that you pass most of it through your digestive tract, without absorption! Studies indicate swallowed THC has a bio-availability of 4-20%.
The CO is not easily absorbed by the body; it bounces off cellular walls, and continues down your tract going 'in one end, and right out the other,' without absorption! Cannabis glandular material is notoriously difficult for the body to absorb, even if it has been activated, and even when it is in the form of a sticky filtered concentrate. It needs a 'vehicle' such as oil, glycerine, or even alcohol, which drastically improves cellular permeability, in order to provide you with the most absorption.

COCONUT OIL. Medium Chained Fatty Acid.
The specific carrier oil source that you choose, directly dictates where in the body, your CO is absorbed. The digestive advantages of MCFAs over long-chain fatty acids (LCFAs) are due to the differences in the way our bodies metabolize these fats. Because the MCFA molecules are smaller, they require less energy and fewer enzymes to break them down for digestion. They are digested and absorbed quickly and with minimal effort. Unlike other fatty acids, MCFAs are absorbed directly from the intestines into the portal vein and sent straight to the liver. (Longer fatty acids are absorbed into the lymphatic system).
Normally you want to keep the cannabinoids away from the liver. The liver metabolizes the CO, causing the majority of the D9-THC to convert to the more psychoactive 11-OH-THC. 11-OH-THC produces a molecule many times more psychoactive but with key medical benefits deactivated.

OLIVE OIL. Long Chain Fatty Acid.
LCFA’s require pancreatic enzymes to break them into smaller units. They are then absorbed into the intestinal wall and packaged into bundles of fat (lipid) and protein called lipoproteins. These lipoproteins are carried by the lymphatic system, bypassing the liver, and then dumped into the bloodstream, where they are circulated throughout the body.

SUMMARY.
Take the oil straight and you are most probably wasting 80%+ as stomach acid will destroy most of its medicinal value, this is why you use a carrier like Coconut oil which takes it from the small intestine straight down the portal vein to the liver. Oil carriers will help it bypass the liver and into the lymphatic system.


In short the whole pharmacogenomics thing means that some people will be genetically predisposed to metabolise THC at different rates and so benefit to differing degrees.

Due to the low and varied bio-availability of oral THC formulations, alternative routes of drug administration, including oromucosal (through the mouth lining), sublingual (under the tongue), vaporization and inhalation, and rectal administration, have been developed by pharmaceutical companies to improve the amount of delivered cannabinoids in their products. All medical user should take note of their measures. This is an industry that would much prefer to produce a usable cannabis pill. That they don't is for good reason.The future of successful Dosing “Competitive Inhibition” Competitive inhibition, allows for greater circulation of cannabinoids through your system. 

This is achieved when certain enzymes in your liver (CYP2C9) are occupied whilst the THC is going through. The metabolism of THC, into 11-OH-THC produces a molecule many times more psychoactive but with ‘key medical benefits deactivated’. It's counter intuitive but the amount of healing occurring cannot easily be judged by the height of the high. THC will be long gone by the time the effects of the 11-OH-THC have stopped being felt.

The enzymes that metabolise cannabinoids are mainly found in the liver. A cannabinoid entering the liver is more likely to connect with an enzyme and be metabolised than to connect with a cancerous cell. Slowing metabolism does not however result in a stronger high. Slowing metabolism of THC to 11-OH-THC means the more psychoactive metabolite's entry into the body is spread out over a longer period. Consequently a person is less likely be made uneasy by a strong more condensed wave of psychoactivity.

Super boosting the Cannabinoids in your system - Methylation

Your receptors can easily become chemically inactivated. They are turned off.
This is called Methylation, basically, methyl groups (cells) surround the receptor sites & shut them down.This is why some people do not experience the full healing effect of the Oil. 

It was proven from a study in 2008 that methyl groups, along with cancer, completely shut down all CB1 receptor sites on cancer patients. We now know that if we can cleanse and activate the receptors that the CO has a strong chance of causing cell death (apoptosis) in cancer.

To Demethylate: 

Daily Routine - Cleaning Cannabinoid Receptors 

Drink Green tea ( I drink at least one cup per day)

Take Omega 3-6 (I take plant based organic oils everyday) 

Drink Grapefruit Juice
Take Polyphenols and Bioflavinoids ( I take flavon 3 times per day)

If you would like to purchase the organic plant based omegas I take or the Flavon then please contact me. 

Essential Oils
I make up these Size 0 capsules containing 5 drops of the essential oil (detailed below) topped up with Virgin Olive Oil. I take one of each of the following twice per day and best to drink lots of water/liquid with them.

5 drops of essential oregano oil topped up with virgin olive oil
(the oregano oil is very potent so I recommend washing your hands after use and its normal to get a heat sensation

after taking it, please note that oregano is a strong anti-fungal so is also very good for cancer just on its own)

5 Drops of essential lemon oil topped up with virgin olive oil
5 Drops of essential Clove oil topped up with virgin olive oil

Here are the links to the supplier I buy my oils

Click for Oregano Oil

Click for Lemon Oil

Click for Clove Oil

30 mins before taking the oil 

Take Mango

Take 1 tablespoon of coconut oil (I heat up the CO in a measuring spoon place in a shot glass then add 1/8th teaspoon of ground cinnamon)

also take these detailed below ...

Competitive Inhibition Considerations: 

The above will reduce rapid clearance of the cannabinoids by 80% or more allowing the cannabinoids greater opportunity to circulate, connect with and destroy mutated cells both in the liver and throughout the body.

The phenolic oils clean methylated receptors and myrcene assists THC across the blood brain barrier. Eating the coconut oil approximately 30 minutes before taking oil by any method will make a big difference. Busy the enzymes themselves and bio-availability might improve by as much as 5 times.

Disclaimer: Please note that I am not a qualified doctor or nutritionist. I am a member of the public that has successfully beaten my own cancer diagnosis. The information on my blogs is in no way intended to diagnose illness or provide medical treatment, it is purely information on the protocol I follow. If you also wish to follow the protocol on my blog and discussed today, you do so entirely at your own risk - please remember to seek and follow your doctors' advice and recommendations at all times.

The information is provided as-is and the blog viewer and todays visitor assumes all risk from the use or misuse of this information. The information on my blog and discussed today is not supported by all conventional medicine practitioners or all physicians.